Diapure 28
Module for PW depyrogenation
| Technical specifications | DiaPure® 28 |
Hollow-fiber material | polysulfone |
Cut off (Da) | 15.000 |
Filtering surface (m2) | 2.8 |
Internal diameter of the fibers (µm) | 250 |
External diameter of the fibers (µm) | 350 |
Thickness of the fiber walls (µm) | 50 |
Fiber length (mm) | 280 |
Number of fibers per filter | 9.600 |
Internal diameter of the housing (mm) | 49.0 |
Potting material | Polyurethane |
Housing and head material | Polycarbonate |
Type of connectors on the container | Hansen |
Type of connector on the head | Hansen |
Module length (mm) | 325 |
Typically, this device is used in the pharmaceutical and biomedical sectors to ultra-filtrate water and aqueous solutions. The filter is mounted downstream of the pre-treatment system, which normally consists of a reverse osmosis system; it ensures a high degree of purity of the liquid, achieving complete removal of bacteria and viruses and a reduction of endotoxin contamination of at least 5 log units.
In these applications, the ultrafiltration elements are periodically subjected to stringent disinfection cycles based on physical processes (recirculation of water in the liquid phase at a temperature of 90 ÷ 95 °C) or chemical processes (circulation of aqueous solutions of sodium hypochlorite, peroxyacetic acid and other disinfectants).
The element can be used as a traditional filter or in a cross-flow filtration regime; in this case purging is carried out continuously or at intervals, to reduce the accumulation of impurities and thus extend the life of the product. Cleaning/sanitization can be done in equi-current or counter-current conditions.
Filtration unit with single modules arranged in parallel layout
As far as flow rates are concerned, the ultra-filtration membrane with a cut-off of approximately 15 kDa fed with a reverse-osmosis permeate is capable of supplying on a continuous basis specific flow rates of 100 l/(h x m2 x bar); as feed pressures of 1-1.5 bar are normally used, a DiaPure® 28 module will provide flow rates of 280-420 l./h. Higher flow rates are obtainable by installing multiple modules in parallel.
The structure of the filtration device consists of three connectors. The first connects the inputs of the filters to the supply pipe of the water to be ultra-filtered; the second connects the output of the filters to the pipe that conveys the ultrapure water to the point of use and the third connects the side connectors, through which it is possible to completely expel the air from the compartment which is external with respect to the fibres in order to carry out proper startups of the filtration system or, alternatively, to perform periodical purges of liquid.
The system features rapid-connection fittings for Hansen couplings in order to facilitate the installation/replacement of individual modules on the ultrapure water manufacturing device. Other types of couplings can be provided according to specific needs.
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